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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRSK2
All Species:
7.58
Human Site:
S678
Identified Species:
18.52
UniProt:
Q8IWQ3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWQ3
NP_003948.2
736
81633
S678
D
V
I
K
Q
L
F
S
D
E
K
N
G
Q
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850919
676
75195
S618
D
V
I
K
Q
L
F
S
D
E
K
N
G
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z98
735
81715
L677
F
F
D
V
I
K
Q
L
F
S
D
E
K
N
G
Rat
Rattus norvegicus
Q8VHF0
797
88733
A729
E
I
R
K
V
L
D
A
N
T
C
D
Y
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA88
798
88848
P724
G
N
S
Q
L
L
Q
P
H
F
F
G
V
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
E1069
D
A
A
D
A
G
M
E
S
D
H
N
G
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648814
861
95238
D794
K
R
Q
V
I
E
N
D
M
E
N
D
S
I
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
D991
F
H
G
K
T
E
K
D
K
G
G
D
D
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
S455
Q
L
H
F
R
D
E
S
S
I
I
E
D
D
C
Baker's Yeast
Sacchar. cerevisiae
P34244
1518
169574
S1277
D
I
L
E
S
S
M
S
Y
S
K
R
R
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
89.8
N.A.
97.9
25.4
N.A.
N.A.
27.4
N.A.
25.1
N.A.
50.9
N.A.
23.1
N.A.
Protein Similarity:
100
N.A.
N.A.
90.3
N.A.
98.7
43.2
N.A.
N.A.
43.9
N.A.
37.9
N.A.
63.5
N.A.
37.3
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
0
13.3
N.A.
N.A.
6.6
N.A.
20
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
0
53.3
N.A.
N.A.
13.3
N.A.
26.6
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.8
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
33.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
10
0
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% C
% Asp:
40
0
10
10
0
10
10
20
20
10
10
30
20
10
0
% D
% Glu:
10
0
0
10
0
20
10
10
0
30
0
20
0
10
0
% E
% Phe:
20
10
0
10
0
0
20
0
10
10
10
0
0
0
10
% F
% Gly:
10
0
10
0
0
10
0
0
0
10
10
10
30
0
20
% G
% His:
0
10
10
0
0
0
0
0
10
0
10
0
0
0
0
% H
% Ile:
0
20
20
0
20
0
0
0
0
10
10
0
0
10
0
% I
% Lys:
10
0
0
40
0
10
10
0
10
0
30
0
10
0
0
% K
% Leu:
0
10
10
0
10
40
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
20
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
10
0
10
30
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% P
% Gln:
10
0
10
10
20
0
20
0
0
0
0
0
0
20
10
% Q
% Arg:
0
10
10
0
10
0
0
0
0
0
0
10
10
0
0
% R
% Ser:
0
0
10
0
10
10
0
40
20
20
0
0
10
20
20
% S
% Thr:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
20
0
20
10
0
0
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _